An old man wearing white shirt sitting and leaning into the wall while holding a bottle of water

Telomere Lengthening via GH Augmentation

In Growth Hormone by Virility, Inc.

Have Scientists Created the Fountain of Youth?
Telomere Lengthening via GH Augmentation is the new Anti-aging Protocol

At 122 years, a French woman died after reaching what experts believe is the absolute ceiling for a human being’s lifetime. The world’s second and third oldest living persons each reached 115 years. Experts in aging sciences theorize that our most likely limit is 115. Like dogs, cats, elephants, Galapagos tortoises, and Amazon grey parrots, we have built-in DNA-governed limits on our lifespans. The French woman is an outlier to the aging formula that is engineered in human DNA/RNA

How GH Triggers an Increase in Telomerase Activity to Defy Aging

As we know, we can’t evade Father Time forever; nevertheless, we do have the biomedical technology to stave off the impact of aging. We have the resources to enable many of us to enjoy decades of youthful vigor, and even live longer. One of the keys to slowing down the aging process, adding more years to our lives, and reducing the probability of suffering age-related disorders, lies in bolstering the levels of the body’s naturally occurring growth hormone (GH). Studies have demonstrated that increased levels of GH combined with the resultant increase in telomerase activity not only delays the aging process but helps our bodies resist cellular degeneration, tumor formation, genetic mutations and many age-related ailments. Together these factors can allow us to live longer, more energetic, and productive lives than ever before.

The long and the short of it? We must lengthen telomeres, which shorten with age, in order to optimize how telomeres and GH interact.

Following are abstracted research studies that shed light on this critical relationship…

Telomeres and GH

Growth Hormone Releasing Hormones (GHRH) such as CJC-1295 and Tesamorelin, and Growth Hormone Releasing Secretagogues such as Ipamorelin are compounds that are used to successfully augment natural growth hormone production. In fact, Tesamorelin is shown to increase IGF-1 levels in men by an average of 181 micrograms/liter and is a powerful GH Releasing Hormone analog that stimulates maximum sustained GH production. Tesamorelin decreases carotid intima media thickness (cIMT), visceral adipose tissue (VAT), and C-reactive proteins (CRP). Tesamorelin has demonstrated improvement in cognitive function for older healthy adults as well as for patients with mild cognitive impairment.

Longevity and Aging

As the medical community knows, human beings enjoy lifespans that cannot last much longer than 115 years. Aging experts expect that enhanced medical technologies will eventually enable genetically sound individuals to live healthy, independent lives until they are nearly 115; however, because of DNA degradation, cellular mutations, and other factors, the body simply wears out.  A person who is healthy and independent at age 113, will probably die by 115 regardless. In fact, the 2nd, 3rd, and 4th longest-living people after the 122-year old French woman were each 115 when they passed away. Consequently, once these advanced medical technologies enable us to drink from the fountain of youth, there is a limit to how long we can drink. However, wouldn’t it be wonderful to live a great life for close to 115 years, rather than experience the low, torturous deterioration that every millennium and baby boomer dreads.

https://www.theatlantic.com/science/archive/2016/10/humans-wont-ever-live-far-beyond-115-years/502967/

The good News is that we do have the technology to live longer, vigorous, independent lives

How GH Works to Resist Aging

Increased GH increases telomerase activity which may be positively correlated with telomere lengthening, resulting in improved longevity and decelerated aging factor that limits cell division.

In other words, more GH increases Telomere length.

Some researchers compare this process to a genetic biological clock. Others liken telomeres to fuses on a biological bomb that becomes shorter and shorter until it greatly distorts the cell’s internal workings.

TELOMERES AND OTHER AGE-RELATED PROBLEMS. Shortened telomeres trigger the aging mechanism for skin, blood, and heart cells. Individuals who suffer a wide range of life-threatening conditions also have shortened telomeres. Among those conditions are hepatitis, and many blood disorders.

The Cancer Conundrum: Our finite cells vs cancer’s seemingly infinite cell life.

If we must deal with a limited lifespan, why do cancer cells go on forever, or so it seems? Anyone who has suffered from cancer wonders how in the world these deranged killer cells continue to spread throughout our bodies, until they choke and kill enough of our normal cells until we can no longer survive. Such is the outcome of most Stage 4 metastatic cancers. How have cancer cells discovered the fountain of youth while we totter on the brink of death almost all of our lives.

It’s complicated…and here’s where telomerase comes in…

In species like mice, telomerase keeps going and going as long as active cells divide, compensating for the mechanisms that cause gradual aging because of replication and cell division.  The answer to this gradual aging are various proteins that are designed to keep the length of telomeres constant.

Viva la difference. Human cells are unique.

Most of our cells pull the plug on telomerase – at least most of them. Consequently, telomeres get shorter and shorter as cells continue dividing. This means telomeres shorten as cells continue to divide.

The trouble is…

More than 85% of  cancer cells possess telomerase. As for the other 15%? They lengthen alternatively.  In other words, some cells lengthen, others don’t.

Summing it up…

Telomerase returns our cells to their youthful vigor by producing certain enzymes. Consequently, the cells with telomerase prevent telomere lengthening for as long as possible. So, if we can live to 122, we have the potential to enjoy vital, independent lives until the very end!