Ipamorelin: First Choice among GH-Secretagogues


Getting to Know About Ipamorelin also known as Pentapeptide


When a physician makes a decision regarding which polypeptide growth hormone will likely be the most beneficial for a particular patient, the doctor must consider several important factors, including:

  • How closely does the polypeptide copy the body’s natural response?
  • Is it more effective than the alternative choices?
  • What are the possible side effects? Can the polypeptide be harmful to the patient? Will it result in the stimulation of undesired substances?
  • Is it easy for the patient to tolerate the particular GH-Secretagogue?

The Verdict
Physicians who specialize in treating patients with leading-edge growth hormone optimization technologies have discovered that Ipamorelin comes out well on the plus side in virtually every beneficial category.

Ipamorelin: A Brief Synopsis
Ipamorelin is a prominent member of the class of peptides known as growth hormone secretagogues. A secretagogue is simply any substance that promotes the secretion of some type of bodily substance. For example, Ipamorelin promotes the secretion of growth hormone (GH). In technical jargon, Ipamorelin is actually a second-generation ghrelin receptor agonist as well as a selective GH-Secretagogue.

Doctors favor Ipamorelin because it creates a long, slow GH pulse that closely resembles your body’s own signaling mechanism. Its ability to stimulate ghrelin is similar to that of GHRP-6, whether it’s used alone or combined with GHRH and GHRP-2, or CJC-1295. However, Ipamorelin has a big advantage over the other ghrelin agonists — it results in much less appetite stimulation. In other words, patients will not feel like they are starving.

Equally important is the fact that unlike other GH-Secretagogues, the Ipamorelin polypeptide does not trigger the creation of undesirable hormones including acetylcholine, aldosterone, cortisol, or prolactin. Consequently, Ipamorelin is often a doctor’s first choice among the GH Secretagogues, and is quoted often.