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Anti-Depressiants and Low-T

In Testosterone by Virility, Inc.

Cause & Effect? The Complex Relationship between Anti-Depressiants and Low-T Anti-depressant medications have provided relief to millions who suffer from depression and other emotional illnesses, although the overall efficacy and benefit of these pharmaceuticals has always been controversial. Empirical and anecdotal evidence points to a relationship between the use of antidepressants, particularly a class known as SSRIs, and the presence …

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Is it Hormones or Depression?

In Testosterone by Virility, Inc.

Tens of millions of Americans are treated for depression with a dizzying array of pharmaceutical medications as well as individual and group therapies. Meantime, researchers and healthcare providers have observed an irrefutable association between the use of antidepressants and low testosterone levels in men (Low-T). Although a cause & effect relationship between antidepressants and testosterone inhibition has not been conclusively …

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Impact of TRT on the Natural Ability to Produce Testosterone

In Testosterone by Virility, Inc.

Some men who undergo testosterone replacement therapy (TRT) worry that the cessation of the therapy can cause harmful side effects, including a compromise in the body’s natural ability to produce testosterone. Because TRT does not stimulate the body to manufacture its own testosterone, testosterone replacement therapy should be considered a long-term, rather than a temporary treatment. Nevertheless, if for whatever …

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Testosterone as a Male Contraceptive?

In Testosterone by Virility, Inc.

Clinical trials conducted since the 1970s indicate that a form of testosterone therapy could have an application as an effective male contraceptive. Following are salient points detailing the results of those clinical trials, as described in a January, 2016 research paper co-authored by Christina Wang, Mario P.R. Festin and Ronald S. Swerdloff: “Male Hormonal Contraception: Where Are We Now?” A …

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Does TRT Cause Prostate Cancer?

In Testosterone by Virility, Inc.

While testosterone can stimulate the spread of existing prostate cancer, studies indicate that it is unlikely that testosterone replacement therapy (TRT) will cause the disease. The relationship between testosterone and prostate cancer is complex. Researchers have tested groups of men who received TRT after being diagnosed with prostate cancer (and presumably cured), as well as TRT groups who enjoyed normal …

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Aromatization and Aromatase Inhibitors

In Testosterone by Virility, Inc.

In the human body, testosterone is converted into estradiol (a type of estrogen) by the enzyme aromatase. This natural process is known as aromatization, and occurs at increased levels in aging males. It also occurs to a higher degree when testosterone is introduced exogenously, with increasing amounts of aromatization occurrence intrinsically linked to elevated levels of testosterone. Aromatization results as …